07202066 is referenced by 1 patents and cites 27 patents.

A composition combining an extracellular matrix-degrading protease and a growth factor related to epithelial cell functions together without inactivation or degradation of the growth factor by the protease. Preferably, the protease is plasmin/plasminogen or a related one, and the growth factor is KGF or a related one. The combination associates two independent, but synergistic functions essential to the re-epithelialization process or healing process, i.e, stimulating epithelial cell proliferation/differentiation and facilitating its migration by clearing the extracellular matrix components. The combination may be constructed in various ways and can be used to treat wounds or any other disease conditions involving cells of epithelial origin or any other cell types that the growth factor may affect.

Title
Combination of a growth factor and a protease enzyme
Application Number
10/59627
Publication Number
7202066 (B2)
Application Date
January 29, 2002
Publication Date
April 10, 2007
Inventor
Kenneth M Yates
Grand Prairie
TX, US
Yawei Ni
College Station
TX, US
Agent
Jackson Walker L
Assignee
Carrington Laboratories
TX, US
IPC
C12N 9/00
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