07176242 is referenced by 43 patents and cites 33 patents.

Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of discorders such as Alzheimer's Disease.

Title
N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
Application Number
10/291318
Publication Number
7176242 (B2)
Application Date
November 8, 2002
Publication Date
February 13, 2007
Inventor
Roy Hom
San Francisco
CA, US
Lawrence Fang
Foster City
CA, US
Ruth TenBrink
Kalamazoo
MI, US
Jennifer Sealy
Burlingame
CA, US
Lakshman Samala
Portage
MI, US
John Mickelson
Mattawan
MI, US
John Freskos
Clayton
MO, US
Andrea Gailunas
Burlingame
CA, US
James Beck
Kalamazoo
MI, US
Barbara Jagodzinska
Redwood City
CA, US
Michel Maillard
Redwood Shores
CA, US
Varghese John
San Francisco
CA, US
Agent
McDonnell Boehnen Hulbert & Berghoff
Assignee
Pharmacia & Upjohn Company
MI, US
Elan Pharmaceuticals
CA, US
IPC
C07C 217/00
A61K 31/133
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