07169378 is referenced by 69 patents and cites 173 patents.

The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a method aspect of the present invention, an opioid is delivered to a patient through an inhalation route. The method comprises: a) heating a thin layer of an opioid, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% opioid degradation products. In a kit aspect of the present invention, a kit for delivering an opioid through an inhalation route is provided which comprises: a) a thin layer of an opioid and b) a device for dispensing said thin layer as a condensation aerosol.

Title
Delivery of opioids through an inhalation route
Application Number
10/768281
Publication Number
7169378 (B2)
Application Date
January 29, 2004
Publication Date
January 30, 2007
Inventor
Alejandro C Zaffaroni
Atherton
CA, US
Joshua D Rabinowitz
Mountain View
CA, US
Agent
Swanson & Bratschun L L C
William L Leschensky
Assignee
Alexza Pharmaceuticals
CA, US
IPC
A61M 15/00
A61K 9/14
A61K 9/12
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