07153265 is referenced by 262 patents and cites 20 patents.

A biosensor including an external surface, and an accessory material in close proximity to the external surface. The accessory material includes a coating containing a hydrophilic material and/or a fiber modified to deliver a therapeutic agent. The biosensor modifies a biological response to the biosensor upon contact with a tissue, such as upon implantation into the skin of a subject, thereby reducing biofouling, inflammation and other undesirable tissue responses that interfere with biosensor performance. The biosensor can be any biocompatible sensor, suitable for short- or long-term use. Preferably, the biosensor is an enzymatic or electrochemical sensor, such as a glucose sensor. Also provided are a method of producing a biosensor and a method of delivering a biologically active substance to a subject.

Title
Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance
Application Number
10/127745
Publication Number
7153265 (B2)
Application Date
April 22, 2002
Publication Date
December 26, 2006
Inventor
David J Vachon
Granada Hills
CA, US
Agent
Gates & Cooper
Assignee
Medtronic MiniMed
CA, US
IPC
A61B 5/00
A61B 5/05
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