07134999 is referenced by 736 patents and cites 251 patents.

An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a curved portion of the body such that when a foreign body capsule forms around the sensor, a contractile force is exerted by the foreign body capsule toward the sensing region. The body is partially or entirely curved, partially or entirely covered with an anchoring material for supporting tissue ingrowth, and designed for subcutaneous tissue implantation. The geometric design, including curvature, shape, and other factors minimize chronic inflammatory response at the sensing region and contribute to improved performance of the sensor in vivo.

Title
Optimized sensor geometry for an implantable glucose sensor
Application Number
10/646333
Publication Number
7134999 (B2)
Application Date
August 22, 2003
Publication Date
November 14, 2006
Inventor
Mark A Tapsak
Orangeville
PA, US
Laura A Martinson
La Mesa
CA, US
Paul V Neale
San Diego
CA, US
Victoria Carr Brendel
San Diego
CA, US
James H Brauker
San Diego
CA, US
Agent
Knobbe Martens Olson & Bear
Assignee
DexCom
CA, US
IPC
A61B 5/00
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