07125693 is referenced by 36 patents and cites 44 patents.

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives.

Title
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
Application Number
10/639159
Publication Number
7125693 (B2)
Application Date
August 11, 2003
Publication Date
October 24, 2006
Inventor
Li A Wang
Palo Alto
CA, US
Roger Sheldon
Rijswijk
NL
Lisa M Newman
Redwood City
CA, US
Steven K Ma
Foster City
CA, US
Gjalt W Huisman
San Carlos
CA, US
John M Gruber
Mountain View
CA, US
David R Gray
Walnut Creek
CA, US
John H Grate
Los Altos
CA, US
S Christopher Davis
San Francisco
CA, US
Agent
Dechert
Assignee
Codexis
CA, US
IPC
C12P 13/00
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