07090830 is referenced by 88 patents and cites 467 patents.

The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1–3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 μm, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided. The device contained in the kit typically, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Also disclosed, are methods for using these aerosols and kits.

Title
Drug condensation aerosols and kits
Application Number
10/718982
Publication Number
7090830 (B2)
Application Date
November 20, 2003
Publication Date
August 15, 2006
Inventor
Martin J Wensley
San Francisco
CA, US
Joshua D Rabinowitz
Mountain View
CA, US
Daniel J Myers
Mountain View
CA, US
Amy T Lu
Los Altos
CA, US
Peter M Lloyd
Walnut Creek
CA, US
Craig C Hodges
Walnut Creek
CA, US
Ron L Hale
Woodside
CA, US
Agent
William L Leschensky
Swanson & Bratschun
Assignee
Alexza Pharmaceuticals
CA, US
IPC
A61M 15/00
A61K 9/14
A61K 9/12
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