07087033 is referenced by 76 patents and cites 40 patents.

One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known is the detection of infiltrated air in the blood line, but this only works in blood lines under negative pressure. According to the invention, a leak detector for return lines is provided by periodically generating a negative pressure, which may be brief or at a 50% duty cycle, in the blood return line to draw air into it and thereby reveal the leaks using an air sensor. Although the return line is ordinarily under positive pressure, during the negative pressure cycle, the blood return line draws air through any leaks or disconnects. If air is detected, the system is shut down and an alarm generated.

Title
Method and apparatus for leak detection in a fluid line
Application Number
10/483142
Publication Number
7087033 (B2)
Application Date
July 8, 2002
Publication Date
August 8, 2006
Inventor
Jeffrey H Burbank
Boxford
MA, US
James M Brugger
Newburyport
MA, US
Agent
Proskauer Rose
Assignee
NxStage Medical
MA, US
IPC
A61M 1/00
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