07081449 is referenced by 43 patents and cites 1 patents.

A purine nucleoside analog includes a pyrido[2,3-d]pyrimidine or a pyrimido[4,5-d]pyrimidine and further has a sugar moiety that is optionally modified at the C2′, C3′, C4′ and/or C5′ position. Particularly contemplated compounds also include prodrug forms of the purine nucleoside analogs, and both purine nucleoside analogs and the corresponding prodrugs are employed in the reduction of growth of neoplastic cells.

Title
Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides
Application Number
10/221397
Publication Number
7081449 (B2)
Application Date
July 3, 2001
Publication Date
July 25, 2006
Inventor
Esmir Gunic
Irvine
CA, US
Jean Luc Girardet
Aliso Viejo
CA, US
Zhi Hong
Aliso Viejo
CA, US
Johnson Lau
Newport Beach
CA, US
Guangyi Wang
Carlsbad
CA, US
Zbigniew Pietrzkowski
San Diego
CA, US
Agent
Brown Raysman Millstein Felder & Steiner
Assignee
Valeant Research & Development
CA, US
IPC
A61K 31/70
A01N 43/04
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