07078019 is referenced by 70 patents and cites 194 patents.

The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a method aspect of the present invention, a drug ester is delivered to a patient through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises a drug ester, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles with less than 5% drug ester degradation product. In a kit aspect of the present invention, a kit for delivering a drug ester through an inhalation route is provided which comprises: a) a thin coating of a drug ester composition and b) a device for dispensing said thin coating as a condensation aerosol.

Title
Delivery of drug esters through an inhalation route
Application Number
10/749783
Publication Number
7078019 (B2)
Application Date
December 30, 2003
Publication Date
July 18, 2006
Inventor
Alejandro C Zaffaroni
Atherton
CA, US
Joshua D Rabinowitz
Mountain View
CA, US
Agent
William L Leschensky
Swanson & Bratschun
Assignee
Alexza Pharmaceuticals
CA, US
IPC
A61M 15/00
A61K 9/14
A61K 9/12
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