07074307 is referenced by 741 patents and cites 94 patents.

The present invention relates generally to systems and methods for improved electrochemical measurement of analytes. The preferred embodiments employ electrode systems including an analyte-measuring electrode for measuring the analyte or the product of an enzyme reaction with the analyte and an auxiliary electrode configured to generate oxygen and/or reduce electrochemical interferants. Oxygen generation by the auxiliary electrode advantageously improves oxygen availability to the enzyme and/or counter electrode; thereby enabling the electrochemical sensors of the preferred embodiments to function even during ischemic conditions. Interferant modification by the auxiliary electrode advantageously renders them substantially non-reactive at the analyte-measuring electrode, thereby reducing or eliminating inaccuracies in the analyte signal due to electrochemical interferants.

Title
Electrode systems for electrochemical sensors
Application Number
10/897312
Publication Number
7074307 (B2)
Application Date
July 21, 2004
Publication Date
July 11, 2006
Inventor
James H Brauker
San Diego
CA, US
Victoria Carr Brendel
Pleasanton
CA, US
James R Petisce
San Diego
CA, US
Peter C Simpson
Del Mar
CA, US
Agent
Knobbe Martens Olson & Bear
Assignee
DexCom
CA, US
IPC
A61B 5/05
G01N 27/327
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