07070765 is referenced by 71 patents and cites 195 patents.

The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a method aspect of the present invention, a drug ester is delivered to a patient through an inhalation route. The method comprises: a) heating a coating of a drug ester, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug ester degradation product. In a kit aspect of the present invention, a kit for delivering a drug ester through an inhalation route is provided which comprises: a) a thin coating of a drug ester composition and b) a device for dispensing said thin coating as a condensation aerosol.

Title
Delivery of drug esters through an inhalation route
Application Number
10/768205
Publication Number
7070765 (B2)
Application Date
January 29, 2004
Publication Date
July 4, 2006
Inventor
Alejandro C Zaffaroni
Atherton
CA, US
Joshua D Rabinowitz
Mountain View
CA, US
Agent
William L Leschensky
Swanson & Bratschun
Assignee
Alexza Pharmaceuticals
CA, US
IPC
A61M 15/00
A61K 9/14
A61K 9/12
View Original Source