07070764 is referenced by 68 patents and cites 190 patents.

The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in inhalation therapy. In a method aspect of the present invention, an analgesic is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of acetaminophen, orphenadrine or tramadol, on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% acetaminophen, orphenadrine or tramadol degradation products. In a kit aspect of the present invention, a kit for delivering acetaminophen, orphenadrine or tramadol through an inhalation is provided which comprises: a) a thin coating of an acetaminophen, orphenadrine or tramadol composition and b) a device for dispensing said thin coating as a condensation aerosol.

Title
Delivery of analgesics through an inhalation route
Application Number
10/766647
Publication Number
7070764 (B2)
Application Date
January 27, 2004
Publication Date
July 4, 2006
Inventor
Alejandro C Zaffaroni
Atherton
CA, US
Joshua D Rabinowitz
Mountain View
CA, US
Agent
William L Leschensky
Swanson & Bratschun
Assignee
Alexza Pharmaceuticals
CA, US
IPC
A61M 15/00
A61K 9/14
A61K 9/12
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