07067144 is referenced by 43 patents and cites 114 patents.

Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.

Title
Compositions and methods for systemic inhibition of cartilage degradation
Application Number
10/356649
Publication Number
7067144 (B2)
Application Date
January 31, 2003
Publication Date
June 27, 2006
Inventor
Jeffrey M Herz
Mill Creek
WA, US
Pamela Pierce Palmer
San Francisco
CA, US
Gregory A Demopulos
Mercer Island
WA, US
Agent
Marcia S Kelbon
Omeros Corporation
Assignee
Omeros Corporation
WA, US
IPC
A61L 9/04
A61F 2/02
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