07060059 is referenced by 458 patents and cites 32 patents.

A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.

Title
System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device
Application Number
10/683466
Publication Number
7060059 (B2)
Application Date
October 14, 2003
Publication Date
June 13, 2006
Inventor
Glenn Vonk
Fuquay-Varina
NC, US
John D DeNuzzio
Chapel Hill
NC, US
Ronald J Pettis
Cary
NC, US
Noel G Harvey
Efland
NC, US
Robert S Parker
Pittsburgh
PA, US
Steven Keith
Chapel Hill
NC, US
Agent
Alan W Fiedler
Assignee
Becton Dickinson and Company
NJ, US
IPC
A61M 31/00
View Original Source