07033608 is referenced by 3 patents and cites 52 patents.

Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1–100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer as a blend of uncapped (free carboxyl end group) and end-capped forms ranging in ratios from 100/0 to 1/99.

Title
“Burst-free” sustained release poly-(lactide/glycolide) microspheres
Application Number
9/337945
Publication Number
7033608 (B1)
Application Date
June 22, 1999
Publication Date
April 25, 2006
Inventor
Jean A Setterstrom
Silver Spring
MD, US
Charles E McQueen
Olney
MD, US
F Donald Roberts
Dover
MA, US
Robert H Reid
Fairfield
PA, US
Phil Friden
Bedford
MA, US
John E Van Hamont
Fort Meade
MD, US
Ramasubbu Jevanthi
Columbia
MD, US
Agent
Elizabeth Arwine
Assignee
The United States of America represented by the Secretary of the Army
DC, US
IPC
A61K 9/50
A61K 9/16
A61K 9/14
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