07010340 is referenced by 96 patents and cites 145 patents.

Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.

Title
Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors
Application Number
10/78310
Publication Number
7010340 (B2)
Application Date
February 18, 2002
Publication Date
March 7, 2006
Inventor
Bahram Ghaffarzadeh Kermani
San Diego
CA, US
Jeffrey Mueller
Winston Salem
NC, US
Lester C Hall
Hollywood
FL, US
H Troy Nagle
Durham
NC, US
Charles W Scarantino
Raleigh
NC, US
Agent
Myers Bigel Sibley & Sajovec PA
Assignee
Sicel Technologies
NC, US
North Carolina State University
NC, US
IPC
A61B 5/07
A61B 6/00
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