07008633 is referenced by 25 patents and cites 16 patents.

Methods regarding local regional treatment in situ for an individual, such as of a tumor, are provided herein. A hydrogel composition is generated in situ in the tumor by administering a polymer, such as a polysaccharide or a polyamino acid, with a therapeutic agent, such as a radionuclide or a drug, and administering a cross-linking agent. The hydrogel/therapeutic agent composition is retained in the tumor for safe and efficient tumor therapy. Alternatively, a hydrogel composition is generated in situ in an artery which nourishes a tumor to occlude the artery.

Title
Local regional chemotherapy and radiotherapy using in situ hydrogel
Application Number
10/24678
Publication Number
7008633 (B2)
Application Date
December 18, 2001
Publication Date
March 7, 2006
Inventor
E Edmund Kim
Houston
TX, US
Tommy L Lee
Spring
TX, US
Ali Azhdarinia
Houston
TX, US
Dong Fang Yu
Houston
TX, US
David J Yang
Sugar Land
TX, US
Agent
Fulbright & Jaworski
Assignee
Board of Regents The University of Texas System
TX, US
IPC
A61K 48/00
A61K 9/14
A61F 13/00
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