07004928 is referenced by 202 patents and cites 146 patents.

The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.

Title
Autonomous, ambulatory analyte monitor or drug delivery device
Application Number
10/131268
Publication Number
7004928 (B2)
Application Date
April 23, 2002
Publication Date
February 28, 2006
Inventor
Peter John Zanzucchi
Princeton Junction
NJ, US
Christopher Carter Gregory
Newton
PA, US
Richard Morgan Moroney III
Princeton
NJ, US
Sterling Eduard McBride
Princeton
NJ, US
John Gregory Aceti
Cranbury
NJ, US
Agent
Patton Boggs L
Assignee
Rosedale Medical
CA, US
IPC
B65D 81/00
A61B 5/00
A61M 5/315
A61M 5/00
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