06955648 is referenced by 53 patents and cites 29 patents.

The present invention relates generally to systems and methods for assessing blood flow in blood vessels, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for adverse effects, and for assessing the effects of risk factors, therapies and substances, including therapeutic substances, on blood vessels, especially cerebral blood vessels, all achieved by measuring various parameters of blood flow in one or more vessels and analyzing the results in a defined matter. The relevant parameters of blood flow include mean flow velocity, systolic acceleration, and pulsatility index. By measuring and analyzing these parameters, one can ascertain the vascular health of a particular vessel, multiple vessels and an individual. Such measurements can also determine whether a substance has an effect, either deleterious or advantageous, on vascular health. In one of many embodiments, the present invention further provides an expert system for achieving the above.

Title
Precision brain blood flow assessment remotely in real time using nanotechnology ultrasound
Application Number
10/359274
Publication Number
6955648 (B2)
Application Date
February 6, 2003
Publication Date
October 18, 2005
Inventor
Simon Fitall
Bethesda
MD, US
John B Davidson
Laytonsville
MD, US
Kevin E Crutchfield
Potomac
MD, US
B Robert Mozayeni
Rockville
MD, US
Agent
Hogan & Hartson
Assignee
New Health Sciences
MD, US
IPC
A61B 008/06
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