06939451 is referenced by 175 patents and cites 84 patents.

A microfluidic device having integrated components for conducting chemical operations. Depending upon the desired application, the components include electrodes for manipulating charged entities, heaters, electrochemical detectors, sensors for temperature, pH, fluid flow, and other useful components. The device may be fabricated from a plastic substrate such as, for example, a substantially saturated norbornene based polymer. The components are integrated into the device by adhering an electrically conductive film to the substrate. The film may be made of metal or an electrically conducting ink and is applied to the device through metal deposition, printing, or other methods for applying films. Methods for reducing bubble formation during electrokinetic separation and methods for heating material in a microfluidic device are also disclosed.

Title
Microfluidic chip having integrated electrodes
Application Number
9/939327
Publication Number
6939451 (B2)
Application Date
August 24, 2001
Publication Date
September 6, 2005
Inventor
Torleif O Bjornson
Gilroy
CA, US
Uyen Nguyen
San Jose
CA, US
Zhu Qun
Mountain View
CA, US
Hilary S Lackritz
Cupertino
CA, US
Antonio Ricco
Los Gatos
CA, US
Petr Vanysek
DeKalb
IL, US
Mingqi Zhao
Cupertino
CA, US
Agent
David Albagli
Stephen C Macevicz
Assignee
Aclara Biosciences
CA, US
IPC
B32B 007/00
G01N 027/447
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