06936467 is referenced by 82 patents and cites 10 patents.

Presented are methods and compositions for targeted chromosomal genomic alterations using modified single-stranded oligonucleotides. The oligonucleotides of the invention have at least one modified nuclease-resistant terminal region comprising phosphorothioate linkages, LNA analogs or 2′-O-Me base analogs.

Title
Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
Application Number
9/818875
Publication Number
6936467 (B2)
Application Date
March 27, 2001
Publication Date
August 30, 2005
Inventor
Michael C Rice
Newtown
PA, US
Howard B Gamper
Philadelphia
PA, US
Eric B Kmiec
Landenberg
PA, US
Agent
Daniel M Becker
Heller Ehrman White & McAuliffe
Assignee
University of Delaware
DE, US
IPC
C12N 015/09
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