06921412 is referenced by 220 patents and cites 34 patents.

Self-supporting, shaped, three-dimensional cross-linked proteinaceous biopolymeric materials that may be implanted in vivo, and methods of making such materials are disclosed. The biopolymeric materials most preferably include reinforcing media, such as biocompatible fibrous or particulate materials. In use, the preformed, shaped biopolymeric materials may be applied to tissue in need of repair and then sealed around its edges with a liquid bioadhesive. In such a manner, repaired tissue which is capable of withstanding physiological pressures may be provided.

Title
Self-supporting, shaped, three-dimensional biopolymeric materials and methods
Application Number
9/570600
Publication Number
6921412 (B1)
Application Date
May 12, 2000
Publication Date
July 26, 2005
Inventor
Aaron J Trygstad
Smyma
GA, US
K Umit Yuksel
Kennesaw
GA, US
Kirby S Black
Acworth
GA, US
Agent
Nixon & Vanderhye P C
Assignee
Cryolife
GA, US
IPC
C12N 011/00
A61L 027/00
A61L 027/00
A61B 017/08
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