06915679 is referenced by 99 patents and cites 30 patents.

Improved microfluidic devices, systems, and methods allow selective transportation of fluids within microfluidic channels of a microfluidic network by applying, controlling, and varying pressures at a plurality of reservoirs. Modeling the microfluidic network as a series of nodes connected together by channel segments and determining the flow resistance characteristics of the channel segments may allow calculation of fluid flows through the channel segments resulting from a given pressure configuration at the reservoirs. To effect a desired flow within a particular channel or series of channels, reservoir pressures may be identified using the network model. Viscometers or other flow sensors may measure flow characteristics within the channels, and the measured flow characteristics can be used to calculate pressures to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems can optionally be used in conjunction with electrokinetic or other fluid transport mechanisms.

Title
Multi-reservoir pressure control system
Application Number
9/792435
Publication Number
6915679 (B2)
Application Date
February 23, 2001
Publication Date
July 12, 2005
Inventor
Anne Kopf Sill
Portola Valley
CA, US
Andrea W Chow
Los Altos
CA, US
J Wallace Parce
Palo Alto
CA, US
Ring Ling Chien
San Jose
CA, US
Agent
Donald R McKenna
Assignee
Caliper Life Sciences
CA, US
IPC
G01N 011/00
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