06858403 is referenced by 142 patents and cites 10 patents.

Hydrogels containing catalase co-immobilized with an analyte-sensitive enzyme such as glucose oxidase are disclosed. The hydrogels may be pH-sensitive, and preferably are thin and lightly crosslinked. The catalase is present in concentrations ranging generally from 100 units/ml to about 1000 units/ml. These hydrogels have much faster swelling response times as compared to hydrogels without catalase, and are useful in biosensors and analyte-responsive drug delivery devices. The hydrogels also have an increased useful life, due to protection of the immobilize analyte-sensitive enzyme from degradation by hydrogen peroxide.

Title
Polymer matrix containing catalase co-immobilized with analytic enzyme that generates hydrogen peroxide
Application Number
9/824552
Publication Number
6858403 (B2)
Application Date
April 2, 2001
Publication Date
February 22, 2005
Inventor
Dal Young Jung
Salt Lake City
UT, US
In Suk Han
Salt Lake City
UT, US
Agent
Robert R Mallinckrodt
Mallinckrodt & Mallinckrodt
Assignee
M Biotech
UT, US
IPC
C12M 001/34
C12N 011/04
C12N 011/18
C12Q 001/54
C12Q 001/30
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