06826422 is referenced by 59 patents and cites 29 patents.

Methods and apparatus are provided for determining a characteristic of a sample of a material by the interaction of electromagnetic radiation with the sample. The apparatus includes an optical assembly and a protective barrier. The optical assembly sequentially illuminates a plurality of volume elements in the sample with an intensity distribution in the sample that drops off substantially monotonically from a first region in a first optical path and collects electromagnetic radiation emanating from each of the volume elements. The optical assembly collects the electromagnetic radiation emanating from each of the volume elements with a collected distribution that drops off substantially monotonically from a second region in a second optical path. The first and second regions at least partially overlap in each of the volume elements. The optical assembly can be configured as a probe, to be directed to the evaluation of a sample of a biological material. A protective barrier can be disposed between the optical assembly and a body tissue, to prevent contamination of the optical assembly by said body tissue.

Title
Spectral volume microprobe arrays
Application Number
9/481762
Publication Number
6826422 (B1)
Application Date
January 11, 2000
Publication Date
November 30, 2004
Inventor
Robert Nordstrom
Hanover
MA, US
Matthew Emans
Boston
MA, US
Jennie Kwo
Cambridge
MA, US
David Lipson
Newton
MA, US
David Bee
Groton
MA, US
Ze&apos ev Hed
Nashua
NH, US
Mark Modell
Natick
MA, US
Agent
Testa Hurwitz & Thibeault
US
Assignee
MediSpectra
MA, US
IPC
A61B 5/05
View Original Source