An active cancellation device receives a model of a first signal from a local wireless transmitter. The first signal causes a coupled signal that interferes in a second signal received by a local wireless receiver from a remote wireless transmitter. The active cancellation device generates a cancellation signal based on the model of the first signal, and provides the cancellation signal to the local wireless receiver. At the local wireless receiver, the cancellation signal combines with the coupled signal and the second signal. The cancellation signal reduces the interference in the second signal caused by the coupled signal.