06730064 is referenced by 314 patents and cites 10 patents.

A coated implantable medical device

10

includes a structure

12

adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer

16

posited on one surface of the structure; and at least one layer

18

of a bioactive material posited on at least a portion of the coating layer

16,

wherein the coating layer

16

provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer

20

can be posited over the bioactive material layer

18,

wherein the porous layer is includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure

12

is a coronary stent. The porous layer

20

includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, and merely by condensation of a monomer vapor.

Title
Coated implantable medical device
Application Number
9/850691
Publication Number
6730064 (B2)
Application Date
May 7, 2001
Publication Date
May 4, 2004
Inventor
Thomas G Kozma
Lafayette
IN, US
William D Voorhees III
West Lafayette
IN, US
Neal E Fearnot
West Lafayette
IN, US
Brian L Bates
Bloomington
IN, US
Anthony O Ragheb
West Lafayette
IN, US
Agent
Richard J Godlewski
US
Assignee
Med Institute
IN, US
Cook Incorporated
IN, US
IPC
A61M 5/32
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