06692724 is referenced by 21 patents.

The invention provides, in a general sense, a new labeling strategy employing

99m

Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to

99m

Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.

Title
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
Application Number
9/434313
Publication Number
6692724 (B1)
Application Date
October 25, 1999
Publication Date
February 17, 2004
Inventor
E Edmond Kim
Houston
TX, US
Dong Fang Yu
Houston
TX, US
Chun W Liu
Sugarland
TX, US
David J Yang
Sugarland
TX, US
Agent
Fulbright & Jaworski L
US
Assignee
Board of Regents The University of Texas System
TX, US
IPC
A61K 51/00
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