06654625 is referenced by 813 patents and cites 85 patents.

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

Title
Mass transport limited in vivo analyte sensor
Application Number
9/595708
Publication Number
6654625 (B1)
Application Date
June 16, 2000
Publication Date
November 25, 2003
Inventor
Adam Heller
Austin
TX, US
Duane O Yamasaki
El Cerrito
CA, US
Hyun Cho
Berkeley
CA, US
Jay D Audett
Mountain View
CA, US
Michael F Tomasco
Danville
CA, US
Henning Sakslund
Pleasant Hill
CA, US
James L Say
Alameda
CA, US
Agent
Merchant & Gould P C
US
Assignee
TheraSense
CA, US
IPC
A61B 5/05
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