06645181 is referenced by 471 patents and cites 15 patents.

The present invention relates to a drug delivery device for mixing and delivering a drug by injection. The device includes a housing having a first port or opening therein that receives a first container that contains a fluid or powdered drug, for example a lyophilized drug. The housing can also include a second port or opening that receives a second container that contains a fluid to be mixed with the drug to form an injectable fluid. The device includes a manifold having a channel that fluidly connects the first and second containers. A penetrating membrane such as a needle is used to inject the drug into a patient which is in fluid communication with the first container. The needle is movable from a storage position in the housing to an injection position extending through the housing.

Title
Drug delivery systems and methods
Application Number
9/439879
Publication Number
6645181 (B1)
Application Date
November 12, 1999
Publication Date
November 11, 2003
Inventor
Joseph Gross
Dublin
US
Izrail Tsals
Sudbury
MA, US
Gil Yigal
Gan-Yavne
US
Gilad Lavi
Holon
US
Agent
Caesar Rivise Bernstein Cohen & Pokotilow
US
Assignee
Elan Pharma International
US
IPC
A61M 5/00
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