06591124 is referenced by 260 patents and cites 28 patents.

A strip-like microneedle device is provided that includes an array of hollow microneedles, a diaphragm pump to extract interstitial fluid from skin, and a sensor that detects the concentration of the fluid. The microneedle device can be interfaced to an external sensor to produce a reading, or can be self-contained. One version uses an attachable/detachable microneedle array as a single-use, disposable unit. The device is portable, and is used by placing one finger on the microneedle array, and actuating the diaphragm pump with another finger, thereby obtaining the fluid sample. Solid coated or transparent microneedles could instead be used as an in-situ sensor, with either electrodes or an optical sensor.

Title
Portable interstitial fluid monitoring system
Application Number
9/853442
Publication Number
6591124 (B2)
Application Date
May 11, 2001
Publication Date
July 8, 2003
Inventor
Chow Chi Huang
West Chester
OH, US
Milan Marcel Jevtitch
Cincinnati
OH, US
Grover David Owens
Fairfield
OH, US
Vladimir Gartstein
Cincinnati
OH, US
Francisco Arias
Cincinnati
OH, US
Faiz Feisal Sherman
West Chester
OH, US
Agent
Bart S Hersko
US
Assignee
The Procter & Gamble Company
OH, US
IPC
A61B 5/05
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