06522926 is referenced by 645 patents and cites 4 patents.

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. By selectively and controllably activating baroreceptors, the present invention reduces excessive blood pressure, sympathetic nervous system activity and neurohormonal activity, thereby minimizing their deleterious effects on the heart, vasculature and other organs and tissues. A baroreceptor activation device is positioned near a baroreceptor, preferably in the carotid sinus and/or the aortic arch. The baroreceptor activation device may comprise a wide variety of devices which utilize mechanical, electrical, thermal, chemical or biological means to activate the baroreceptor. A control system may be used to generate a control signal to modulate the baroreceptor activation device. A sensor may be used to generate a signal indicative of cardiovascular function or other organ system function, and the control signal may be made a function of the sensor signal. The control system may include a processor and a memory, wherein the memory includes software containing an algorithm defining a relationship between the control signal and the sensor signal. The present invention also provides devices, systems and methods to selectively and controllably increase blood pressure, nervous system activity, and neurohormonal activity by inhibiting/dampening baroreceptor signals.

Title
Devices and methods for cardiovascular reflex control
Application Number
9/671850
Publication Number
6522926 (B1)
Application Date
September 27, 2000
Publication Date
February 18, 2003
Inventor
Gina L Hansen
Maple Grove
MN, US
Thomas R Hektner
Medina
MN, US
Matthew M Burns
Orono
MN, US
Peter T Keith
St. Paul
MN, US
Robert S Kieval
Medina
MN, US
Agent
Townsend and Townsend and Crew
US
Assignee
CVRx
MN, US
IPC
A61N 1/18
View Original Source