06509034 is referenced by 12 patents.

This invention concerns wettable microcapsules ethylcellulose coated cores and to processes for their preparation; in particular, to microcapsules with ethylcellulose coats that are wettable so that they are suspendable in aqueous medium. The wettable microcapsules can be prepared by applying ethylcellulose onto drug containing core by phase separation from a solvent to provide microcapsules, optionally washing said microcapsules with a solvent in which said microcapsules are substantially insoluble and drying, (a) one or more surfactants is/are incorporated in the solvent at the phase separation step; and/or (b) one or more surfactants is/are incorporated in the solvent used to wash the microcapsules; and/or said microcapsules being coated with one or more surfactants optionally in the presence of a binder.

Title
Wettable microcapsules having hydrophobic polymer coated cores
Application Number
9/673178
Publication Number
6509034 (B1)
Application Date
October 10, 2000
Publication Date
January 21, 2003
Inventor
Luigi Giovanni Mapelli
Milan
US
Leonardo Gentilini
Milan
US
Stefano De Luigi Bruschi
Milan
US
Massimo Maria Calanchi
Sesto s. Giovanni
US
Agent
Thompson Hine
US
Assignee
Eurand International S p A
US
IPC
A61K 9/50
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