06503231 is referenced by 369 patents and cites 14 patents.

Microneedle devices for transport of therapeutic and diagnostic materials and/or energy across tissue barriers, and methods for manufacturing the devices, are provided. The microneedles are hollow and/or porous and have diameters between about 10 nm and 1 mm. The microneedle devices permit drug delivery (or removal or sensing of body fluids) at clinically relevant rates across skin or other tissue barriers, without damage, pain, or irritation to the tissue. Microfabrication techniques are used to cost-effectively produce arrays of microneedles from metals, silicon, silicon dioxide, ceramic, and polymeric materials. Methods are provided for making porous or hollow microneedles.

Title
Microneedle device for transport of molecules across tissue
Application Number
9/95221
Publication Number
6503231 (B1)
Application Date
June 10, 1998
Publication Date
January 7, 2003
Inventor
Sebastien Henry
Ay
US
Devin V McAllister
Holley
NY, US
Mark G Allen
Atlanta
GA, US
Mark R Prausnitz
Atlanta
GA, US
Agent
Ropes & Gray
US
Assignee
Georgia Tech Research Corporation
GA, US
IPC
A61M 5/32
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