06485413 is referenced by 683 patents and cites 19 patents.

An imaging system for performing forward scanning imaging for application to therapeutic and diagnostic devises used in medical procedures. The imaging system includes forward directed optical coherence tomography (OCT), and non-retroreflected forward scanning OCT. Also interferometric imaging and ranging techniques and fluorescent, Raman, two-photon, and diffuse wave imaging can be used. The forward scanning mechanisms include a cam attached to a motor, pneumatic devices, a pivoting device, piezoelectric transducers, electrostatic driven slides for substantially transverse scanning; counter-rotating prisms, and offset lenses are used for arbitrary scanning. The imaging system of the invention is applied to hand held probes including probes integrated with surgical probes, scalpels, scissors, forceps and biopsy instruments. Hand held probes include forward scanning lasers. The imaging system is also applicable to laparoscopes and endoscopes for diagnostc and therapeutic intervention in body orifices, canals, tubes, ducts, vessels and cavities of the body. The imaging system includes application to surgical and high numerical aperture microscopes. An important application of the invention is implantation of the optical probe for periodic or continuous extraction of information from the tissue site where implanted.

Title
Methods and apparatus for forward-directed optical scanning instruments
Application Number
9/36283
Publication Number
6485413 (B1)
Application Date
March 6, 1998
Publication Date
November 26, 2002
Inventor
Eric A Swanson
Acton
MA, US
James G Fujimoto
Cambridge
MA, US
Mark E Brezinski
Malden
MA, US
Brett E Bouma
Boston
MA, US
Gary J Tearney
Cambridge
MA, US
Stephen A Boppart
Boston
MA, US
Agent
Testa Hurwitz & Thibeault
US
Assignee
The General Hospital Corporation
MA, US
IPC
A61B 1/06
View Original Source