06480733 is referenced by 414 patents.

A method for monitoring the progression of the hemodynamic status of a heart failure patient. An implantable or other ambulatory monitor senses the patient's electrocardiogram (ECG) and calculates R-R intervals. The R-R intervals are used to calculate a measure of heart rate variability (HRV). Significant excursions from the average of the HRV measure are indicative of a heart failure exacerbation. Alternatively, vascular plethysmography provides a measure of pulse amplitude. Significant reduction in pulse amplitude and pulse amplitude variability are indicative of a heart failure exacerbation. This information may be used to warn the patient or healthcare providers of changes in the patient's condition warranting attention.

Title
Method for monitoring heart failure
Application Number
9/467298
Publication Number
6480733 (B1)
Application Date
December 17, 1999
Publication Date
November 12, 2002
Inventor
Robert Turcott
Menlo Park
CA, US
Agent
Steven M Mitchell
US
Assignee
Pacesetter
CA, US
IPC
A61B 5/0452
View Original Source