06427082 is referenced by 22 patents.

A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and the backscatter response to illumination by white light (in the spectral range of 360 to 750 nm). Combining LIF and white light responses, as well as evaluating a spatial correlation between proximate cervical tissue sites in conjunction with a statistically significant “distance” algorithm, such as the Mahalanobis distance between data sets, can improve the discrimination between normal and abnormal tissue. The results may be displayed in the form of a map of the cervix representing the suspected pathology.

Title
Optical methods and systems for rapid screening of the cervix
Application Number
9/471700
Publication Number
6427082 (B1)
Application Date
December 23, 1999
Publication Date
July 30, 2002
Inventor
Mark Modell
Natick
MA, US
Robert Nordstrom
Hanover
MA, US
Agent
Testa Hurwitz & Thibeault
US
Assignee
MediSpectra Incorporated
MA, US
IPC
A61B 6/00
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