06366813 is referenced by 500 patents.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more intracranial (IC) stimulating electrodes in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition. Neural modulation signals include any control signal which enhances or inhibits cell activity. Significantly the neurological control system considers neural response, in the form of the sensory feedback, as an indication of neurological disease state and/or responsiveness to therapy, in the determination of treatment parameters.

Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
Application Number
Publication Number
6366813 (B1)
Application Date
June 25, 1999
Publication Date
April 2, 2002
Daniel J DiLorenzo
155 First Ave., Suite 5, Salt Lake City
Lloyd W Sadler
A61N 1/00
View Original Source