06358556 is referenced by 461 patents and cites 11 patents.

A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.

Title
Drug release stent coating
Application Number
9/12443
Publication Number
6358556 (B1)
Application Date
January 23, 1998
Publication Date
March 19, 2002
Inventor
Michael N Helmus
Long Beach
CA, US
Ni Ding
Plymouth
MN, US
Assignee
Boston Scientific Corporation
MA, US
IPC
B05D 3/04
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