06358236 is referenced by 86 patents and cites 2 patents.

A device is provided for reconstituting a lyophilized or powdered medicament such as blood factor VIII which must be reconstituted just prior to use, such as by introduction of a sterile fluid from a syringe, which comprises a housing having an upper section capable of receiving a syringe and a lower section capable of receiving a vial containing the medicament in co-axial alignment with the syringe, a middle section connecting the upper and lower sections which has a central aperture which forms a passageway for fluid transfer between the syringe and the vial, and a hollow vented spike which extends downwardly from the central aperture for a length sufficient to ensure that the lower end of the spike will pierce the seal and enter the interior of a vial housed in the lower section of the device. The invention is advantageous because the vented opening in the spike will allow for an equalization of the pressure after the piercing of the vial by the spike which will facilitate the use of the device. In addition, the device also features an ergonomic design which maximizes the safety and efficiency of the reconstitution of important medicaments such as blood factors, and allows for easily manipulation of the device by patients such as those with Factor VIII deficiency who may suffer from related physical ailments which limit their dexterity.

Title
Device for reconstituting medicaments for injection
Application Number
9/129898
Publication Number
6358236 (B1)
Application Date
August 6, 1998
Publication Date
March 19, 2002
Inventor
Ingrid McPhilliamy
Chicago
IL, US
Arnold Bilstad
Deerfield
IL, US
John Mark DeFoggi
Waukegan
IL, US
Agent
Larson & Taylor
US
Assignee
Baxter International
IL, US
IPC
A61B 19/00
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