06342503 is referenced by 65 patents and cites 16 patents.

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer'disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula:

wherein R

1

, R

3

, R

4

, R

5

, Z, Y, V, X, X′, J, K, L, and M are as defined herein.

Title
1N-alkyl-n-arylpyrimidinamines and derivatives thereof
Application Number
9/4150
Publication Number
6342503 (B1)
Application Date
January 7, 1998
Publication Date
January 29, 2002
Inventor
Zelda Rakowitz Wasserman
Wilmington
DE, US
Sang William Tam
Boston
MA, US
Everett Latham Scholfield
New Castle
DE, US
Paul John Krenitsky
Newark
DE, US
Carl Nicholas Hodge
Wilmington
DE, US
Dimitri Emil Grigoriadis
Carlsbad
CA, US
Paul Joseph Gilligan
Wilmington
DE, US
Thomas Eugene Christos
Oxford
PA, US
Robert John Chorvat
West Chester
PA, US
Robert Scott Cheeseman
Phoenixville
PA, US
Argyrios Georgios Arvanitis
Kennett Square
PA, US
Paul Edward Aldrich
Wilmington
DE, US
Agent
Kalim S Fuzail
US
Kenneth B Rubin
US
Robert W Black
US
Assignee
DuPont Pharmaceuticals Company
DE, US
IPC
C07D 239/42
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