06331415 is referenced by 343 patents and cites 53 patents.

The invention relates to processes for producing an immunoglobulin or an immunologically functional immunoglobulin fragment containing at least the variable domains of the immunoglobulin heavy and light chains. The processes can use one or more vectors which produce both the heavy and light chains or fragments thereof in a single cell. The invention also relates to the vectors used to produce the immunoglobulin or fragment, and to cells transformed with the vectors.

Title
Methods of producing immunoglobulins, vectors and transformed host cells for use therein
Application Number
7/205419
Publication Number
6331415 (B1)
Application Date
June 10, 1988
Publication Date
December 18, 2001
Inventor
Ronald B Wetzel
San Francisco
CA, US
Arthur D Riggs
La Verne
CA, US
William E Holmes
Pacifica
CA, US
Herbert L Heyneker
Burlingame
CA, US
Shmuel Cabilly
Monrovia
CA, US
Agent
Burns Doane Swecker & Mathis
US
Assignee
Genentech
CA, US
IPC
C12N 15/13
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