06325798 is referenced by 268 patents and cites 168 patents.

Systems and methods treat a tissue region at or near a sphincter by deploying a carrier, which carries an electrode that can be advanced to penetrate tissue. Negative pressure is applied through a suction port on the carrier near the electrode, to draw tissue in the tissue region inward against the carrier. The systems and methods advance the electrode to penetrate tissue drawn against the carrier. The vacuum anchors the surrounding tissue and mediates against the “tenting” of tissue during electrode penetration. Without tenting, the electrode penetrates mucosal tissue fully, to obtain a desired depth of penetration.

Title
Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions
Application Number
9/304743
Publication Number
6325798 (B1)
Application Date
May 4, 1999
Publication Date
December 4, 2001
Inventor
Ronald Lax
Daytona Beach
FL, US
Jay Chin
Fremont
CA, US
Scott West
Livermore
CA, US
David Utley
San Carlos
CA, US
John Gaiser
Mountain View
CA, US
Stuart Edwards
Portola Valley
CA, US
Agent
Ryan Kromholz & Manion S C
US
Assignee
Curon Medical
CA, US
IPC
A61B 18/18
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