06319466 is referenced by 34 patents and cites 28 patents.

A test device for detecting the presence of a residue analyte in a sample includes a support strip and a sample-absorbing matrix attached to the support strip. The sample-absorbing matrix has a material for absorbing an amount of the sample. The test device also includes a mobile-phase support for holding a mobile-phase composition. The mobile-phase support is attached to the support strip and in contact with the sample-absorbing matrix. A mobile-phase composition is disposed on the mobile-phase support and has a receptor for binding with the analyte. The mobile-phase composition can be carried in the sample. A stationary-phase membrane is attached to the support strip and has a first membrane end in contact with the mobile-phase composition and a second membrane end. The membrane allows lateral capillary flow of the sample from the first membrane end to the second membrane end. A test zone is on the stationary-phase membrane between the first membrane end and second membrane end and having a first binder for binding with an unbound receptor. A control zone is the stationary-phase a membrane between the test zone and second membrane end and has a second binder for binding with an analyte-bound receptor or residual unbound receptor.

Title
Test device for detecting the presence of a residue analyte in a sample
Application Number
9/118135
Publication Number
6319466 (B1)
Application Date
July 16, 1998
Publication Date
November 20, 2001
Inventor
Eliezer Zomer
Newton
MA, US
Shefali B Trivedi
Quincy
MA, US
Richard T Skiffington
North Reading
MA, US
Joan L Scheemaker
Chelmsford
MA, US
Steven J Saul
Arlington
MA, US
Yael Agi Glickman
Moshav Tsofit
US
Paul R Donahue
Southboro
MA, US
Stanley E Charm
Boston
MA, US
Cheryl A Boyer
Malden
MA, US
Robert J Markovsky
Amesbury
MA, US
Agent
IP Legal Strategies Group P C
US
Agent
Leslie Meyer Leon Esq
US
Assignee
Charm Sciences
MA, US
IPC
G01N 21/78
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