06296702 is referenced by 33 patents and cites 42 patents.

The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongate fiber is disposed within the tube for axial movement therein between raised and lowered positions. Upon shifting or oscillating the fiber between its raised and lowered positions, a liquid spot can be formed at a selected position on the substrate. The device is readily adaptable for the production of micro-arrays having a great number of individual spots.

Title
Apparatus and method for spotting a substrate
Application Number
9/270218
Publication Number
6296702 (B1)
Application Date
March 15, 1999
Publication Date
October 2, 2001
Inventor
Charles S Vann
Fremont
CA, US
Zbigniew Bryning
Campbell
CA, US
Agent
Jeffrey D Frazier
US
Assignee
PE Corporation
CA, US
IPC
B05C 5/00
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