06268161 is referenced by 455 patents and cites 18 patents.

A biosensor (

10

) has a pH-sensitive polymeric hydrogel (

30

) in a rigid and preferably biocompatible enclosure (

20

). The hydrogel (

30

) includes an immobilized oxidoreductase enzyme such as glucose oxidase. The oxidoreductase enzyme catalyzes a chemical reaction consuming an organic molecule and producing a byproduct. The hydrogel (

30

) changes its osmotic pressure in proportion to the concentration of a byproduct. By measuring the change in osmotic pressure with a pressure transducer (

40

), the biosensor (

10

) is able to accurately measure the concentration of the organic molecule without the problem of interference encountered by prior art biosensors. A battery (

64

) powered telemeter (

60

) operably engaged to the pressure transducer (

40

) sends a radio data signal to a receiver (

66

) operably attached to a computer (

62

).

Title
Biosensor
Application Number
9/308392
Publication Number
6268161 (B1)
Application Date
May 11, 1999
Publication Date
July 31, 2001
Inventor
Seong Gi Baek
Woodbury
MN, US
Jules J Magda
Salt Lake City
UT, US
You Han Bae
Salt Lake City
UT, US
In Suk Han
Salt Lake City
UT, US
Agent
Morriss Bateman O&apos Bryant & Compagni
US
Assignee
M Biotech
UT, US
IPC
C12Q 1/54
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