06262107 is referenced by 64 patents and cites 26 patents.

Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.

Title
Water soluble paclitaxel prodrugs
Application Number
9/346263
Publication Number
6262107 (B1)
Application Date
July 1, 1999
Publication Date
July 17, 2001
Inventor
David J Yang
Sugar Land
TX, US
Dong Fang Yu
Houston
TX, US
Sidney Wallace
Houston
TX, US
Chun Li
Missouri City
TX, US
Agent
Foley & Lardner
US
Assignee
PG TXL Company
TX, US
IPC
A01N 43/02
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