06258121 is referenced by 455 patents and cites 190 patents.

A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating includes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a second, lower rate over a longer time period. One stent coating utilizes a faster releasing hydrophilic polymeric material and a slower releasing hydrophobic material. One stent coating includes a blend of a faster releasing PLA-PEO copolymer and a slower releasing PLA-PCL copolymer. One active agent is Taxol. One use of the Taxol delivering stent is to inhibit restenosis following angioplasty.

Title
Stent coating
Application Number
9/346975
Publication Number
6258121 (B1)
Application Date
July 2, 1999
Publication Date
July 10, 2001
Inventor
Scott R Smith
Chaska
MN, US
Lixiao Wang
Maple Grove
MN, US
Joel L Stanslaski
New Hope
MN, US
Dachuan Yang
Plymouth
MN, US
Agent
Crompton Seager & Tufte
US
Assignee
SciMed Life Systems
MN, US
IPC
A61F 2/06
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