06254550 is referenced by 206 patents and cites 57 patents.

A preformed anchoring wire guide (

10

) for medical procedures such as renal angioplasty. The wire guide (

10

) is comprised of a superelastic memory alloy mandril (

11

), such as a nickel-titanium alloy, and includes a preformed bend (

14

) having an angle (

15

) with respect to the longitudinal axis (

28

) that corresponds with the takeoff angle of the renal artery (

23

) relative to the aorta (

33

). This preformed bend (

14

) allows easier access to the ostium (

22

) of the renal artery (

23

) and allows the distal portion (

27

) of the wire guide to anchor within the artery (

23

) and resist dislodgement and deformation, thereby improving trackability of a balloon angioplasty catheter (

21

), reducing the need for a guiding catheter, and reducing the likelihood of vessel damage or thrombus shear due to forces that are normally exerted against the wall of the vessel (

33

) by a standard wire guide. The wire guide has a tapered distal portion (

20

) over which a spring coil wire (

16

) is attached to provide radiopacity and safety to the vasculature. The distal portion (

27

) of the wire guide is flexible and is further made atraumatic by the addition of a hook-shaped or ā€œJā€ tip (

29

). Additionally, the nickel-titanium alloy mandril is cold-worked in its austenitic phase at preformed bend (

14

) by overstressing the wire in a fixture, thereby shifting at least part of the crystalline structure to martensite within the region of the preformed bend (

14

).

Title
Preformed wire guide
Application Number
9/377293
Publication Number
6254550 (B1)
Application Date
August 19, 1999
Publication Date
July 3, 2001
Inventor
Edward J Morris
Bloomington
IN, US
Beth A Kirts
Bloomington
IN, US
Thomas O McNamara
Los Angeles
CA, US
Agent
Anton P Ness
US
Richard J Godlewski
US
Assignee
Cook Incorporated
IN, US
IPC
A61B 5/00
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